IPO4

Importin-4 is a protein that in humans is encoded by the IPO4 gene.

IPO4
Identifiers
Aliases	IPO4, Imp4, importin 4
External IDs	MGI: 1923001; HomoloGene: 5835; GeneCards: IPO4; OMA:IPO4 - orthologs
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14 C3|14 28.19 cM Start 55,862,857 bp End 55,873,414 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas gastrocnemius muscle right uterine tube right adrenal gland sural nerve anterior pituitary left adrenal gland kidney skeletal muscle tissue bone marrow cells Top expressed in internal carotid artery external carotid artery seminiferous tubule fossa Gonadal ridge condyle vas deferens morula arcuate nucleus paraventricular nucleus of hypothalamus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding nuclear localization sequence binding Cellular component cytoplasm nuclear membrane nuclear pore membrane nuclear periphery nucleus protein-containing complex Biological process protein transport DNA replication-dependent chromatin assembly intracellular protein transport ribosomal protein import into nucleus NLS-bearing protein import into nucleus transport protein import into nucleus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79711 75751 Ensembl n/a ENSMUSG00000002319 UniProt Q8TEX9 Q8VI75 RefSeq (mRNA) NM_024658 NM_024267 NM_001360078 RefSeq (protein) NP_078934 NP_077229 NP_001347007 Location (UCSC) n/a Chr 14: 55.86 – 55.87 Mb PubMed search
Wikidata
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Further reading

• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
• Miyauchi Y, Michigami T, Sakaguchi N, et al. (2006). "Importin 4 is responsible for ligand-independent nuclear translocation of vitamin D receptor". J. Biol. Chem. 280 (49): 40901–8. doi:10.1074/jbc.M509347200. PMID 16207705.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Lischka P, Sorg G, Kann M, et al. (2003). "A Nonconventional Nuclear Localization Signal within the UL84 Protein of Human Cytomegalovirus Mediates Nuclear Import via the Importin α/β Pathway". J. Virol. 77 (6): 3734–48. doi:10.1128/JVI.77.6.3734-3748.2003. PMC 149505. PMID 12610148.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.