Hrinchenko is a surname. Notable people with the surname include:
- Andriy Hrinchenko (born 1986), Ukrainian footballer
- Borys Hrinchenko (1863–1910), Ukrainian writer, activist, historian, publicist and ethnographer
- Maria Hrinchenko (1863–1928), Ukrainian folklorist
- Mykola Hrinchenko (born 1986), Ukrainian footballer
- Vladyslav Hrinchenko (born 1989), Ukrainian footballer