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Emil Fischer

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Hermann Emil Louis Fischer FRS FRSE FCS (9 October 1852 – 15 July 1919) was a German chemist and 1902 recipient of the Nobel Prize in Chemistry. He discovered the Fischer esterification. He also developed the Fischer projection, a symbolic way of drawing asymmetric carbon atoms. He never used his first given name, and was known throughout his life simply as Emil Fischer.[2][3][4][5]

Hermann Emil Fischer
Hermann Emil Fischer c1895.jpg
Hermann Emil Fischer
Born
Hermann Emil Louis Fischer

(1852-10-09)9 October 1852
Died15 July 1919(1919-07-15) (aged 66)
NationalityGermany
Alma materUniversity of Bonn
University of Strasbourg
Known forStudy of sugars & purines
Awards
Scientific career
FieldsChemistry
InstitutionsUniversity of Munich (1875–81)
University of Erlangen (1881–88)
University of Würzburg (1888–92)
University of Berlin (1892–1919)
Doctoral advisorAdolf von Baeyer[citation needed]
Doctoral studentsAlfred Stock
Otto Diels
Otto Ruff
Walter A. Jacobs
Ludwig Knorr
Oskar Piloty
Julius Tafel

Contents

Early yearsEdit

Fischer was born in Euskirchen, near Cologne, the son of Laurenz Fischer, a businessman, and his wife Julie Poensgen. After graduating he wished to study natural sciences, but his father compelled him to work in the family business until determining that his son was unsuitable. Fischer then attended the University of Bonn in 1871, but switched to the University of Strasbourg in 1872.[6] He earned his doctorate in 1874 under Adolf von Baeyer[6] with his study of phthaleins and was appointed to a position at the university.

ResearchEdit

Fischer is noted for his work on sugars: among other work, the organic synthesis of D-(+)-glucose[7] and purines (including the first synthesis of caffeine).

Fischer was also instrumental in the discovery of barbiturates, a class of sedative drugs used for insomnia, epilepsy, anxiety, and anesthesia. Along with the physician Josef von Mering, he helped to launch the first barbiturate sedative, barbital, in 1904.[8]

Honours, awards, and legacyEdit

ReferencesEdit

  1. ^ a b "Fellows of the Royal Society". London: Royal Society. Archived from the original on 2015-03-16.
  2. ^ Horst Kunz (2002). "Emil Fischer – Unequalled Classicist, Master of Organic Chemistry Research, and Inspired Trailblazer of Biological Chemistry". Angewandte Chemie International Edition. 41 (23): 4439–4451. doi:10.1002/1521-3773(20021202)41:23<4439::AID-ANIE4439>3.0.CO;2-6. PMID 12458504.
  3. ^ Lichtenthaler, F. W. (1992). "Emil Fischers Beweis der Konfiguration von Zuckern: eine Würdigung nach hundert Jahren". Angewandte Chemie. 104 (12): 1577–1593. doi:10.1002/ange.19921041204.
  4. ^ Forster, Martin Onslow (1 January 1920). "Emil Fischer memorial lecture". Journal of the Chemical Society, Transactions. 117: 1157–1201. doi:10.1039/CT9201701157.
  5. ^ Biography Biography of Fischer from Nobelprize.org website
  6. ^ a b Eduard, Farber (1970–80). "Fischer, Emil Hermann". Dictionary of Scientific Biography. 5. New York: Charles Scribner's Sons. pp. 1–5. ISBN 978-0-684-10114-9.
  7. ^ Fischer, Emil (1890). "Synthese des Traubenzuckers". Berichte der deutschen chemischen Gesellschaft. 23: 799–805. doi:10.1002/cber.189002301126.
  8. ^ López-Muñoz, Francisco; Ucha-Udabe, Ronaldo; Alamo, Cecilio (2005). "The history of barbiturates a century after their clinical introduction". Neuropsychiatric disease and treatment. 1 (4): 329–43. PMC 2424120. Retrieved 2 December 2018.

External linksEdit