In molecular biology, Hydatidiform mole associated and imprinted (non-protein coding), also known as HYMAI, is a long non-coding RNA. It is an imprinted gene, which is paternally expressed.[1] Overexpression of HYMAI and the protein-coding gene PLAG1 causes transient neonatal diabetes mellitus type 1 (TNDM1).[2]

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References

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  1. ^ Arima T, Drewell RA, Oshimura M, Wake N, Surani MA (2000). "A novel imprinted gene, HYMAI, is located within an imprinted domain on human chromosome 6 containing ZAC". Genomics. 67 (3): 248–255. doi:10.1006/geno.2000.6266. PMID 10936046.
  2. ^ Mackay DJ, Temple IK (2010). "Transient neonatal diabetes mellitus type 1". Am J Med Genet C Semin Med Genet. 154C (3): 335–342. doi:10.1002/ajmg.c.30272. PMID 20803656.

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