HME may refer to:
- HME, Incorporated, a U.S. custom truck manufacturer
- Hereditary multiple exostoses
- Human monocytotropic ehrlichiosis, an infectious disease
- Home medical equipment
- Hamble railway station, in England
- Heat and moisture exchanger
- Human macrophage metalloelastase, an enzyme
- Hot melt extrusion
- Hermes Aviation, a defunct airline of Malta
- Home market effect
- Huishui Miao, a language of China
- Homemade explosive, often used in improvised explosive devices
- Oued Irara–Krim Belkacem Airport, in Algeria
- Humen railway station, China Railway pinyin code HME
This disambiguation page lists articles associated with the title HME.
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