HGSC may refer to:
- Harvard Gender and Sexuality Caucus (formerly Harvard Gay and Lesbian Caucus), American non-profit organization of LGBT alumni/ae, faculty, staff and students
- Human Genome Sequencing Center, human genetics center at Baylor College of Medicine in Houston, Texas
- High-grade serous carcinoma, a type of epithelial tumour that makes up the majority of ovarian cancer cases
This disambiguation page lists articles associated with the title HGSC.
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