Governor Columbus may refer to:
- Bartholomew Columbus (1460s–1515), Governor of Santo Domingo in the 1490s
- Christopher Columbus (1451–1506), 1st Governor of the Indies from 1492 to 1499
- Diego Columbus (died 1526), 4th Governor of the Indies from 1509 to 1518
This disambiguation page lists articles associated with the title Governor Columbus.
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