Glycoprotein endo-alpha-1,2-mannosidase
(Redirected from Glycoprotein endo-a-1,2-mannosidase)
Glycoprotein endo-α-1,2-mannosidase (EC 3.2.1.130, glucosylmannosidase, endo-α-D-mannosidase, endo-α-mannosidase, endomannosidase, glucosyl mannosidase) is an enzyme with systematic name glycoprotein glucosylmannohydrolase.[1][2] It catalyses the hydrolysis of the terminal α-D-glucosyl-(1,3)-D-mannosyl unit from the GlcMan9(GlcNAc)2 oligosaccharide component of the glycoprotein produced in the Golgi membrane.
| Glycoprotein endo-α-1,2-mannosidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.2.1.130 | ||||||||
| CAS no. | 108022-16-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This protein is involved in the synthesis of glycoproteins.
See also edit
References edit
- ^ Lubas WA, Spiro RG (March 1987). "Golgi endo-α-D-mannosidase from rat liver, a novel N-linked carbohydrate unit processing enzyme". The Journal of Biological Chemistry. 262 (8): 3775–81. PMID 3818665.
- ^ Tulsiani DR, Coleman VD, Touster O (February 1990). "Asparagine-linked glycoprotein biosynthesis in rat brain: identification of glucosidase I, glucosidase II, and endomannosidase (glucosyl mannosidase)". Archives of Biochemistry and Biophysics. 277 (1): 114–21. doi:10.1016/0003-9861(90)90558-g. PMID 2407194.
External links edit
- Glycoprotein+endo-alpha-1,2-mannosidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
