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Girinimbine is a carbazole alkaloid isolated from the curry tree (Murraya koenigii) along with the related alkaloids mahanimbine,[1] koenimbine,[2] isomahanine, mahanine, and others.

Girinimbine
Girinimbine structure
Names
IUPAC name
3,3,5-Trimethyl-11H-pyrano[3,2-a]carbazole
Other names
Girinimbin
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
Properties
C18H17NO
Molar mass 263.340 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

A 2011 study of girinimbine found that it inhibited the growth and induced apoptosis in human hepatocellular carcinoma, HepG2 cells in vitro.[3]

ReferencesEdit

  1. ^ CID 167963 from PubChem
  2. ^ Metabocard for Koenimbine
  3. ^ Syam, Suvitha; Abdul, Ahmad Bustamam; Sukari, Mohd. Aspollah; Mohan, Syam; Abdelwahab, Siddig Ibrahim; Wah, Tang Sook (2011). "The Growth Suppressing Effects of Girinimbine on Hepg2 Involve Induction of Apoptosis and Cell Cycle Arrest". Molecules. 16 (8): 7155–70. doi:10.3390/molecules16087155. PMID 21862957.