GenePeeks is a genetic research company that owns and runs Matchright, a simulation that determines the probability of genetic disorders being present in a child given two people's DNA.
| Founders | Anne Morriss Lee Silver |
|---|---|
| Location | |
| Website | web |
Overview
editGenePeeks simulates the combination of genetic sequences of two people and predicts potential diseases and inherited disorders to find good recipient matches for sperm donors.[1] By simulating the process of reproduction with the two DNA sequences, the company's software (called Matchright) forms a hypothetical child genome to determine the likelihood of the resulting child developing one of around 600 conditions.[1][2] The technology is currently aimed at sperm banks; the first users will be at two fertility clinics in the United States, one of which is Manhattan Cryobank in New York City.[1][3]
The software creates around 10,000 virtual genomes for each donor-recipient pair, and typically rules out 10-15% of donors as bad matches for the recipient.[4] Currently it only searches for single gene genetic conditions, but the company plan to expand the software to look for multiple gene diseases like diabetes and heart disease.[4]
Concern has been raised as to whether the software would allow "designer babies", but the company say that they are not intending to use the system for non-medical purposes.[4][5]
History
editGenePeeks was established by Anne Morriss and Lee Silver. Silver is a genetics professor at Princeton University whose work is focused on reproduction and development.[1][4] Morriss was motivated to start the service in part by her own experience of starting a family; her son received an inherited disorder (MCADD) after being conceived with sperm from a donor.[6] The two started GenePeeks after being introduced by a mutual friend.[4]
In January 2014 the company was issued a patent for their algorithms to simulate genetic interactions.[7]
In October 2018, Anne Morriss had left the company and the company website has since been taken down.[8][9]
References
edit- ^ a b c d Rincon, Paul (October 4, 2013). "Genepeeks firm to offer 'digital baby' screen for sperm donors". BBC News. Retrieved April 16, 2014.
- ^ Rojahn, Susan (November 20, 2012). "Genetic Screening Can Uncover Risky Matches at the Sperm Bank". MIT Technology Review. Retrieved April 16, 2014.
- ^ Mohney, Gillian (April 10, 2014). "New Tech Allows Parents Genetic 'Preview' Before Conception". ABC News.
- ^ a b c d e de Lange, Catherine (April 6, 2014). "Startup offering DNA screening of 'hypothetical babies' raises fears over designer children". The Guardian. Retrieved April 16, 2014.
- ^ de Lange, Catherine (April 12, 2014). "Meet your unborn child - before it's conceived". New Scientist. Retrieved April 16, 2014.
- ^ Johnson, Carolyn (October 14, 2013). "Company seeks to make sperm banks safer". Boston Globe. Retrieved April 16, 2014.
- ^ "GenePeeks Announces Issuance of US Patent for Pre-Conception Prediction of Disease Risk in Hypothetical Future Children". Business Wire. January 27, 2014. Retrieved April 16, 2014.
- ^ "Homepage". GenePeeks. Archived from the original on October 2, 2018.
- ^ "No such app". Archived from the original on October 30, 2018.
External links
edit- Official website October 2, 2018 archive