Gamache is a surname. Notable people with the surname include:
- Joey Gamache (born 1966), American boxer
- Justinne Gamache, American singer
- Simon Gamache (born 1981), Canadian ice hockey player
Fictional characters
edit- Henri Gamache, pseudonym of an otherwise unknown folk magic author of the 1940s
- Chief Inspector Armand Gamache, the main character in a series of mystery novels written by Canadian author Louise Penny