Gaius Betitius Pius (c. 175 - after 223) was a Patronus of Canusium in 223.

He was the son of Gaius Betitius Maximillianus (born c. 145), Suffect Consul.

He married Seia Fuscinilla (born c. 185), sister of Seius Sallustius, Roman usurper Emperor, daughter of Seius (born c. 155) and wife Herennia Orbiana (born c. 160), and paternal granddaughter of Publius Seius Fuscianus (c. 120 - after 189), Consul in 151?, PUR 187-189 and Suffect Consul in 188, and had:

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