Fratangelo is an Italian surname. Notable people with the surname include:

  • Bjorn Fratangelo (born 1993), American tennis player
  • Dawn Fratangelo, American reporter based in New York City for NBC News
  • Michael Fratangelo (born 1977), American Visual Artist based in Pittsburgh, PA known for his Spiritually symbolic portriats, "IRAQ-Paintings of War" 2005 series and "Refugee" 2024 series graduate of The Pennsylvania State University 2001