FERM, RhoGEF and pleckstrin domain-containing protein 2 is a protein that in humans is encoded by the FARP2 gene.[5][6][7]

FARP2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFARP2, FIR, FRG, PLEKHC3, FERM, ARH/RhoGEF and pleckstrin domain protein 2
External IDsOMIM: 617586; MGI: 2385126; HomoloGene: 8877; GeneCards: FARP2; OMA:FARP2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001282983
NM_001282984
NM_014808

NM_145519

RefSeq (protein)

NP_001269912
NP_001269913
NP_055623

NP_663494

Location (UCSC)Chr 2: 241.36 – 241.49 MbChr 1: 93.44 – 93.55 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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FARP2 has been shown to interact with PDZK1.[8]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000006607Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034066Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
  6. ^ Kubo T, Yamashita T, Yamaguchi A, Sumimoto H, Hosokawa K, Tohyama M (Oct 2002). "A novel FERM domain including guanine nucleotide exchange factor is involved in Rac signaling and regulates neurite remodeling". The Journal of Neuroscience. 22 (19): 8504–13. doi:10.1523/JNEUROSCI.22-19-08504.2002. PMC 6757789. PMID 12351724.
  7. ^ "Entrez Gene: FARP2 FERM, RhoGEF and pleckstrin domain protein 2".
  8. ^ Gisler SM, Pribanic S, Bacic D, Forrer P, Gantenbein A, Sabourin LA, Tsuji A, Zhao ZS, Manser E, Biber J, Murer H (Nov 2003). "PDZK1: I. a major scaffolder in brush borders of proximal tubular cells". Kidney International. 64 (5): 1733–45. doi:10.1046/j.1523-1755.2003.00266.x. PMID 14531806.

Further reading

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  • Overview of all the structural information available in the PDB for UniProt: Q91VS8 (FERM, ARHGEF and pleckstrin domain-containing protein 2) at the PDBe-KB.