Fairbrother is a surname. Notable people with the surname include:
- Barrie Fairbrother, (born 1950), English football player
- Helen Fairbrother, English winner of the Miss International crown
- Ian Fairbrother (born 1966), English football player
- John Fairbrother (born 1941), English footballer
- Jack Fairbrother (1917–1999), English football goalkeeper
- Keith Fairbrother (born 1944), English chairman and rugby union player of Coventry RFC
- Nan Fairbrother (1913–1971), English writer and lecturer on landscape and land use
- Neil Fairbrother (born 1963), English cricket player
- Nicola Fairbrother (born 1970), judoka from England
- Russell Fairbrother, New Zealand lawyer and politician
- Sarah Fairbrother (1816–1890), English actress and the mistress of Prince George, Duke of Cambridge
- Sydney Fairbrother (1872–1941), British actress
- Tim Fairbrother (born 1982), New Zealand rugby union player
- Tony Fairbrother (1926–2004), aeronautical engineer, flight test engineering on the maiden flight of the de Havilland Comet, the first jet airliner