||Named for Aramingo Borough whose name was a corruption of the Lenni Lenapi stream name Tumanaraming, meaning "Wolf Walk."|
||Originally Baltimore Pike, named for the destination city of Baltimore, Maryland
||Named for John Blair.|
||As with "Broad Street" in various other towns and cities, it was named for its breadth, and laid out and developed as a central thoroughfare.
|Cecil B. Moore Avenue
||Named in honor of the late Philadelphia civil rights attorney Cecil B. Moore, who led the fight to integrate Girard College, president of the local NAACP, and member of Philadelphia's City Council. Was formerly called Columbia Avenue.
||Named for Hannah Callowhill Penn, William Penn's second wife and acting proprietor of the colony of Pennsylvania from 1712 to 1726.
||Follows the border between Cheltenham Township, Montgomery County and Philadelphia County.
||One of William Penn's streets named for trees, this one was named for the cherry tree.
||One of William Penn's streets named for trees, this one was named for the chestnut tree.
||Named after Chief Justice of the Supreme Court of Province of Pennsylvania, Benjamin Chew
||The street is also U.S. 1, and its name refers to its role as both the Philadelphia city line and the Montgomery County line.
||Formerly Delaware Avenue because it ran along the Delaware River. Renamed in honor of explorer Christopher Columbus upon the 500th anniversary of his famous 1492 voyage, as requested by various Italian Americans of South Philadelphia.
||Named for John Dickinson, Continental Congressman and one of the signers of the Constitution.
||Named after Jeremiah Elfreth, an 18th-century blacksmith and property owner. It is one of the oldest continuously inhabited residential streets in the United States of America, dating to 1702.
||The road between two Federal properties, the Philadelphia Navy Yard and the Schuylkill Arsenal|
|Benjamin Franklin Parkway
||Named for Benjamin Franklin.
||Like "Front Street" in various other towns and cities, it was named after a riverfront, in this case the Delaware riverfront, which for several centuries was the economic and social heart of the city.
||It was the road to Germantown back when Germantown was a separate town, several miles outside Philadelphia.
|Girard Avenue, Girard Point, and Girard Point Bridge
||Named for financier Stephen Girard.
|Independence Mall East, Independence Mall West
||Named for Independence Mall, the district whose heart is Independence Hall.
||Formerly East River Drive, because it runs along the east bank of the Schuylkill River, it was renamed in honor of Olympic athlete John B. Kelly Jr..|
|John F. Kennedy Boulevard
||Built in the 1950s as part of the large redevelopment of the Pennsylvania Railroad "Chinese Wall" and former Broad Street Station that created Penn Center; it was for several years called Pennsylvania Boulevard before being renamed for John F. Kennedy after his assassination. It serves as part of Pennsylvania Route 3.
||Originally Lancaster Pike, named for the destination city of Lancaster, Pennsylvania.
||One of William Penn's streets named for trees, this one was named for the locust tree.
||As with "Market Street" in many other towns and cities, it was for several centuries the main market site.
||The neighborhood's name comes from the word "manaiung," place where we go to drink, in the language of the Lenape|
|Martin Luther King Jr. Drive
||Formerly called West River Drive because it runs along the west bank of the Schuylkill River, it was renamed in honor of slain civil rights leader Martin Luther King Jr.
|Mount Pleasant Drive
||Named for the historic mansion Mount Pleasant, built in what was then the countryside outside of the city by a privateer. It is now an off-premises gallery of the Philadelphia Museum of Art in Fairmount Park.|
||Named for Lenni Lenape word meaning "pigeon droppings."|
| Old York Road, York Road, King's Highway
||The old road to New York City was named, as was that city and its province, for James, Duke of York (later James II & VII.)
||Named for the Lenape word meaning "in the valley; in the Valleys."|
||Named for the county line between Philadelphia and Montgomery counties, which it runs along for part of its route (Phil + Mont).
||One of William Penn's streets named for trees, this one was named for the pine tree.
||Race Street was originally called Sassafras Street and until the mid-19th century was often used as a horse race track—the era's equivalent of today's street racing. Eventually the name Race Street became the official name.
||Named for Joseph Reed, statesmen of the American Revolution.
||Named for the ridge of high ground between the Wissahickon and Schuylkill valleys, which the avenue follows.
|Rising Sun Avenue
||Named after the Rising Sun Tavern, which was an important roadhouse in colonial times.
|Roosevelt Boulevard/Roosevelt Expressway
||Named for President Theodore Roosevelt.
||Named by developer William Sansom for himself (See Jewelers' Row)
||Named for the historic village where the Shackamaxon Treaty was signed between William Penn and the village leaders of the Delaware/Lenape Indian tribe.
||Formerly known as Cedar Street (originally one of William Penn's streets named for trees, in this case cedar trees), it is the original southern border of the city of Philadelphia, before the 1854 Act of Consolidation.
||One of William Penn's streets named for trees, this one was named for the spruce tree.
||One of William Penn's streets named for trees, this one was named for the walnut tree.
||One of William Penn's streets named for trees, this one was named after vines.