Esta Sterneck is an Austrian molecular biologist researching the functions of the C/EBPδ][CEBPD transcription factor as tumor suppressor as well as tumor promoter in breast epithelial cells and cells of the tumor microenvironment. She is a senior investigator and head of the molecular mechanisms in development section at the National Cancer Institute.
Esta Sterneck | |
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| Born | G. Esta Sterneck |
| Alma mater | Heidelberg University (PhD) |
| Scientific career | |
| Fields | Molecular biology, cancer research |
| Institutions | National Cancer Institute |
| Thesis | Mechanismus der Aktivierung von cMGF-Produktion durch Kinasen in Transformierten Myeloiden Zellen (1991) |
Education
editEsta Sterneck trained at the European Molecular Biology Laboratory and the Center for Molecular Biology Heidelberg University before completing a Ph.D. at Heidelberg University. Her thesis work investigated oncogene cooperation in leukemia cells and revealed their coordinate induction of an essential autocrine growth factor.[1] Her 1991 thesis was titled, Mechanismus der Aktivierung von cMGF-Produktion durch Kinasen in Transformierten Myeloiden Zellen.[2]
During her postdoctoral training at the Advanced BioScience Laboratories-Basic Research Program in Frederick, Maryland. Sterneck began to study the functions of CCAAT-enhancer-binding proteins (C/EBP) transcription factors, including their roles in normal mammary gland development, through genetically engineered mice.[1]
Career and research
editSterneck began her independent research with an NCI-Scholar grant before being recruited as a principal investigator to the National Cancer Institute (NCI) in 2003. She is a senior investigator and head of the molecular mechanisms in development section.[1]
Sterneck's research investigates signaling pathways with emphasis on pro-inflammatory molecules in breast epithelial cells and cells of the tumor microenvironment. She studies cell signaling pathways that regulate mammary gland development and tumorigenesis.[1]
Awards and honors
editIn 2013, Sterneck received the NIH Merit Award and the NCI Outstanding Mentor Award.[1]
References
edit- ^ a b c d e "Esta Sterneck, Ph.D." Center for Cancer Research. 2014-08-12. Retrieved 2020-05-09.
This article incorporates text from this source, which is in the public domain.
- ^ Sterneck, Esta (1991). Mechanismus der Aktivierung von cMGF-Produktion durch Kinasen in Transformierten Myeloiden Zellen (Thesis) (in German). Heidelberg University. OCLC 75257374.
External links
edit- Esta Sterneck publications indexed by Google Scholar
This article incorporates public domain material from websites or documents of the National Institutes of Health.