Erminio "Mimo" Costa (March 9, 1924 – November 28, 2009) was an Italian-American neuroscientist.[3] His research interests covered brain serotonergic activity in health and disease, benzodiazepine-GABA interactions,[4] benzodiazepine action at GABAA receptors, neurophysiological role of neurosteroids,[5] and GABAergic dysfunction and changes in the expression of reelin and GAD67 in schizophrenia.[6] He published more than 1,000 articles.[7] The June 2011 issue of the journal Neuropharmacology was dedicated to him.[8]
Erminio Costa | |
|---|---|
| Born | March 9, 1924 |
| Died | November 28, 2009 (aged 85)[1] Chevy Chase, Maryland, U.S. |
| Nationality | Italian |
| Citizenship | American |
| Alma mater | University of Cagliari |
| Known for | Research on serotonin, the GABA receptor, and metabotropic glutamate receptors |
| Spouse | Ingeborg Hanbauer |
| Children | Michael, Max and Robert (Robert died in 2006)[2] |
| Scientific career | |
| Fields | Neuropharmacology |
| Institutions | Columbia University, Georgetown University |
Career edit
- July 1947 - M.D. 110/110 cum laude, University of Cagliari, Italy
- 1950-1960 - Thudichum Psychiatric Research Laboratory, Galesburg Research Hospital, Galesburg, Illinois
- 1960-1965 - Deputy Chief, Laboratory of Chemical Pharmacology at NHLI - NIH, Bethesda, Maryland
- 1965-1968 - Associate Professor of Pharmacology and Neurology, College of Physicians and Surgeons of Columbia University, New York, NY
- 1968-1985 - Chief of the Laboratory of Preclinical Pharmacology, NIMH, St. Elizabeths Hospital, Washington, DC
- 1985-1994 - Director and Founder, Institute of Neuroscience, and Professor of Pharmacology, Georgetown University, Washington, DC
- 1994-1995 - Director, Center for Neuropharmacology, Nathan Kline Institute for Psychiatric Research, New York University, New York, NY
- 1995 - Scientific Director, Psychiatric Institute, Professor of Biochemistry in Psychiatry, Department of Psychiatry, College of Medicine, University of Illinois at Chicago, Chicago, Illinois
- 1982 - Member, National Academy of Sciences
- 1991 - Member of "Accademia dei Lincei" founded by Galileo Galilei in 1602, Rome
Books edit
- Advances in Biochemical Psychopharmacology (1969)
- Biochemistry and Pharmacology of the Basal Ganglia (1966)
- Biochemistry of Simple Neuronal Models (1970)
- Neurosteroids and Brain Function (1991)
- The Endorphins - Vol. 18 (1985)
See also edit
- Bernard Brodie, in whose laboratory Costa worked for a time.
References edit
- ^ Social Security Death Index, 1935-2014. Social Security Administration.
- ^ Grayson, D. R.; Guidotti, A. (2010). "Erminio Costa". Neuropsychopharmacology. 35 (13): 2646. doi:10.1038/npp.2009.231. PMC 3055564.
- ^ Clayton, Paula J.; Fatemi, S. Hossein (2008). The medical basis of psychiatry. Totowa, NJ: Humana Press. ISBN 1-58829-917-1.
- ^ Barondes, Samuel H. (2003). Better than Prozac: Creating the next generation of psychiatric drugs. Oxford [Oxfordshire]: Oxford University Press. ISBN 0-19-515130-5.
- ^ Pinna, G.; Uzunova, V.; Matsumoto, K.; Puia, G.; Mienville, J. M.; Costa, E.; Guidotti, A. (2000-01-28). "Brain allopregnanolone regulates the potency of the GABA(A) receptor agonist muscimol". Neuropharmacology. 39 (3): 440–448. doi:10.1016/s0028-3908(99)00149-5. ISSN 0028-3908. PMID 10698010.
- ^ Costa E, Chen Y, Davis J, Dong E, Noh JS, Tremolizzo L, Veldic M, Grayson DR, Guidotti A (February 2002). "REELIN and schizophrenia: a disease at the interface of the genome and the epigenome". Mol. Interv. 2 (1): 47–57. doi:10.1124/mi.2.1.47. PMID 14993361. Archived from the original on 2013-04-14.
- ^ "UIC, Dept. of Psychiatry News: Erminio Costa, M.D., Logs 1,000th Publication". Archived from the original on 30 April 2004.
- ^ Bloom FE (June 2011). "Mentored and inspired by Mimo: a tribute to Erminio Costa". Neuropharmacology. 60 (7–8): 1003–6. doi:10.1016/j.neuropharm.2010.09.019. PMID 20869374.