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Epimysium (plural epimysia[1]) (Greek epi- for on, upon, or above + Greek mys for muscle) is the fibrous tissue envelope that surrounds skeletal muscle.[2] It is a layer of dense irregular connective tissue which ensheaths the entire muscle and protects muscles from friction against other muscles and bones.[3] It is continuous with fascia and other connective tissue wrappings of muscle including the endomysium and perimysium. It is also continuous with tendons, where it becomes thicker and collagenous.

Illu muscle structure.jpg
Structure of a skeletal muscle (epimysium labeled at bottom center)
LocationSkeletal muscle
Anatomical terminology

While the epimysium is irregular on muscles, it is regular on tendons.

See alsoEdit


  1. ^ "Definition of "Epimysia" from". Retrieved 2008-05-29.
  2. ^ "Definition of epimysium on the Merriam-Webster Dictionary". The Merriam-Webster Dictionary. Retrieved 29 July 2015.
  3. ^ McCracken, Thomas (1999). New Atlas of Human Anatomy. China: Metro Books. pp. 1–120. ISBN 1-5866-3097-0.