Eosinophilic (Greek suffix -phil-, meaning loves eosin) refers to the staining of certain tissues, cells, or organelles after they have been washed with eosin, a dye.

A basophil granulocyte is surrounded by lightly staining eosinophilic erythrocytes in an H&E staining.

Eosin is an acidic dye; thus, the structure being stained is basic and as a corollary, is acidophilic.

Eosinophilic describes the appearance of cells and structures seen in histological sections that take up the staining dye eosin. This is a bright-pink dye that stains the cytoplasm of cells, as well as extracellular proteins such as collagen.[1]

Such eosinophilic structures are, in general, composed of protein.

The stain eosin is usually combined with a stain called hematoxylin to produce a hematoxylin- and eosin-stained section (also called an H&E stain, HE or H+E section). This is the most widely used histological stain in medical diagnosis; for example, when a pathologist examines a biopsy of a suspected cancer, the biopsy will have been stained with H&E.

Some structures seen inside cells are described as being eosinophilic, for example, Lewy and Mallory bodies.[2] Some cells are also described as eosinophilic, such as Leukocytes.[3]

See alsoEdit


  1. ^ About Eosinophilic Disorders. Children's Hospital of Philadelphia. Accessed March 2nd, 2012
  2. ^ Eosinophilic. Medline Plus. Accessed March 2nd, 2012.
  3. ^ Dixon, Frank J. (1986). Advances in Immunology, Volume 39. Academic Press. p. 323. ISBN 9780120224395.