Elizabeth Duke may refer to:
- Elizabeth Ashburn Duke (born 1952), member of the Board of Governors of the Federal Reserve System
- Elizabeth Ann Duke (born 1940), wanted FBI domestic terrorist fugitive
- Elizabeth Duke (administrator), former administrator for the Health Resources and Services Administration (HRSA)
- Elizabeth Duke (author), pen name of Vivienne Wallington
- Elizabeth Duke, a brand owned by Argos, formerly used for its jewellery range
This disambiguation page lists articles about people with the same name.
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