Endoprotease B, isoform 2 (EP-B2) is a cysteine protease found in barley. In studies, it has shown promise as a possible therapeutic for coeliac disease.[1] Aspergillopepsin from Aspergillus niger has been shown to enhance the effects of EP-B2.[2]

References Edit

  1. ^ Vora, H.; McIntire, J.; Kumar, P.; Deshpande, M.; Khosla, C. (2007). "A scaleable manufacturing process for pro-EP-B2, a cysteine protease from barley indicated for celiac sprue". Biotechnology and Bioengineering. 98 (1): 177–185. doi:10.1002/bit.21423. PMID 17385743. S2CID 19581223.
  2. ^ Ehren, J.; Morón, B.; Martin, E.; Bethune, M.; Gray, G.; Khosla, C.; El-Shemy, H. A. (2009). "A food-grade enzyme preparation with modest gluten detoxification properties". PLOS ONE. 4 (7): e6313. Bibcode:2009PLoSO...4.6313E. doi:10.1371/journal.pone.0006313. PMC 2708912. PMID 19621078.

Further reading Edit