Ectonucleoside triphosphate diphosphohydrolase 6 is an enzyme that in humans is encoded by the ENTPD6 gene.[5][6]

ENTPD6
Identifiers
AliasesENTPD6, CD39L2, IL-6SAG, IL6ST2, NTPDase-6, dJ738P15.3, ectonucleoside triphosphate diphosphohydrolase 6 (putative), ectonucleoside triphosphate diphosphohydrolase 6
External IDsOMIM: 603160; MGI: 1202295; HomoloGene: 68170; GeneCards: ENTPD6; OMA:ENTPD6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_172117
NM_001355068

RefSeq (protein)

NP_742115
NP_001341997
NP_001357558
NP_001357559
NP_001357560

Location (UCSC)Chr 20: 25.2 – 25.23 MbChr 2: 150.75 – 150.77 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions, which is characteristic of NTPases.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000197586Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033068Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Chadwick BP, Frischauf AM (Jun 1998). "The CD39-like gene family: identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster". Genomics. 50 (3): 357–67. doi:10.1006/geno.1998.5317. PMID 9676430.
  6. ^ a b "Entrez Gene: ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative function)".

Further reading

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