Engulfment and cell motility protein 2 is a protein that in humans is encoded by the ELMO2 gene .[ 5] [ 6]
The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein. Similarity to a C. elegans protein suggests that this protein may function in phagocytosis of apoptotic cells and in cell migration . Alternative splicing results in multiple transcript variants encoding the same protein.[ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000062598 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017670 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS (Oct 2001). "CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration" (PDF) . Cell . 107 (1): 27–41. doi :10.1016/S0092-8674(01)00520-7 . PMID 11595183 . S2CID 15232864 . Archived from the original (PDF) on 2021-09-22. Retrieved 2020-08-31 . ^ a b "Entrez Gene: ELMO2 engulfment and cell motility 2" .
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