E55 may refer to:
- European route E55
- Mercedes-Benz E55 AMG, a performance car
- M113 E55, a version of the Mercedes-Benz M113 engine
- The Nokia E55 mobile phone
- Nimzo-Indian Defense, Encyclopaedia of Chess Openings code
- Ocean Ridge Airport (FAA code E55)
- Tokushima-Nanbu Expressway, Anan-Aki Expressway and Kōchi-Tōbu Expressway, route E55 in Japan
- E55 road in United Arab Emirates, from Umm al-Quwain to Al Shuwaib.
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