Marc E. Rothenberg (born 1961) is an American physician-scientist who has made significant contributions to the fields of allergy, gastroenterology, and immunology. He is currently a Professor of Pediatrics, at Cincinnati Children's Hospital Medical Center, and the University of Cincinnati College of Medicine, the Director of the Division of Allergy and Immunology, the Director of the Cincinnati Center for Eosinophilic Disorders,[2] and the principal investigator of the Consortium of Eosinophilic Disease Researchers (CEGIR)[3] as part of the Rare Disease Clinical Research Network of the National Institute of Health.[4] Rothenberg's research is focused on eosinophilic gastrointestinal diseases.[5]

Marc E. Rothenberg
Born (1961-01-17) January 17, 1961 (age 63)[1]
Forest Hills, NY
EducationBrandeis University; Harvard Medical School
TitleProfessor of Pediatrics;

Director, Division of Allergy and Immunology at Cincinnati Children's Hospital Medical Center;

Director, Cincinnati Center for Eosinophilic Disorders

Early life and education

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Rothenberg was born in New York City in 1961. He received his Bachelor of Arts degree in Biochemistry and Chemistry from Brandeis University in 1983. His undergraduate years were influences by the renowned biochemist Professor William P. Jencks, who was Rothenberg’s early research mentor.[6] He went on to earn his medical degree and PhD in Immunology from Harvard Medical School in 1990, conducting research under the mentorship of Professor K. Frank Austen.[6] He completed his residency in pediatrics at Boston Children's Hospital and his fellowship in Allergy and Immunology and Hematology at Boston Children’s Hospital and the Dana Farber Cancer Institute.[2]

Career

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Rothenberg began his career as a faculty member at the University of Cincinnati College of Medicine and Cincinnati Children's Hospital Medical Center in 1996, where he has since remained.[2] Rothenberg established the Cincinnati Center for Eosinophilic Disorders, a center focused on eosinophilic diseases.[7]

In 2016, Rothenberg was the first recipient of the Denise and Dave Bunning Chair for Allergy and Immunology.[8]

Rothenberg is also the current Director of the NIH-sponsored Consortium of Eosinophilic Gastrointestinal Disease Researchers, part of the Rare Diseases Clinical Research Network.[3] In 2021, he was elected Co-Chair of the RDCRN.[9]

Research

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The Rothenberg CURED Laboratory at Cincinnati Children's Hospital Medical Center conducts research focused on the molecular analysis of allergic inflammation, particularly the pathogenesis of eosinophilic gastrointestinal disorders.[10] His research is credited with elucidating the mechanism of eosinophilia, including the identification of key checkpoints that are central targets for therapeutic intervention. These targets have been translated into developed clinical products. Rothenberg's research has included key proof-of-principle studies that provided the bases for a new class of drugs, anti-eosinophil therapeutics, as well as the first FDA approved drug for eosinophilic esophagitis.

Awards and honors

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Rothenberg has been recognized for his contributions to science and medicine with numerous honors and awards, including the American Academy of Allergy, Asthma, and Immunology (AAAAI) Distinguished Scientist Award,[11] the National Institutes of Health (NIH) Merit Award,[12] the E. Mead Johnson Award from the Society of Pediatric Research,[13] and the Paul Ehrlich Award[14] from the International Eosinophil Society. Rothenberg was also recognized as a Highly Cited Researcher in 2018 (Clarivate Analytics).[15] He is an elected member of the American Society for Clinical Investigation,[16] the Association of American Physicians and the National Academy of Medicine.[17][18] In 2023, Rothenberg was awarded the Daniel Drake Medal for his impact on the field of Allergy and Immunology.[19]

Publications

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Rothenberg has authored and co-authored over 500 peer-reviewed articles.[20][21]

References

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  1. ^ "Rothenberg, Marc E., 1961- - LC Linked Data Service: Authorities and Vocabularies | Library of Congress, from LC Linked Data Service: Authorities and Vocabularies (Library of Congress)". Library of Congress. Retrieved 1 July 2022.
  2. ^ a b c "Marc E. Rothenberg, MD, PhD". www.cincinnatichildrens.org. Retrieved 2021-12-16.
  3. ^ a b "Scientist Spotlight: Marc Rothenberg Leads Eosinophilic Collaboration and Research to New Discoveries". Rare Diseases Clinical Research Network. Retrieved 2021-12-16.
  4. ^ "Rare Diseases Clinical Research Network".
  5. ^ "Rothenberg CURED Lab". Cincinnati Children's Hospital. Retrieved 2021-12-16.
  6. ^ a b "Rothenberg Named to National Academy of Medicine". 17 October 2022.
  7. ^ "Eosinophilic Gastrointestinal Disorders | Rothenberg Laboratory Current Projects". www.cincinnatichildrens.org. Retrieved 2021-12-16.
  8. ^ "Marc Rothenberg Receives First Bunning Chair Cincinnati Children's". www.cincinnatichildrens.org. Retrieved 2021-12-16.
  9. ^ "RDCRN Announces New 2021 Network Steering Committee Leadership". Rare Diseases Clinical Research Network. Retrieved 2021-12-16.
  10. ^ "Eosinophilic Gastrointestinal Disorders | Rothenberg Laboratory Current Projects". www.cincinnatichildrens.org. Retrieved 2022-04-30.
  11. ^ "2023 AAAAI Honorary Award Recipients".
  12. ^ "Doctor at Cincinnati Children's receives prestigious NIH MERIT Award to extend research of eosinophilic gastrointestinal disorders". www.cincinnatichildrens.org. Retrieved 2021-12-16.
  13. ^ "Past Award Recipients – Society for Pediatric Research". Retrieved 2022-04-30.
  14. ^ "Dr. Rothenberg received the Paul Ehrlich Lectureship Award". Rare Diseases Clinical Research Network. Retrieved 2022-03-31.
  15. ^ "Clarivate Analytics Highly Cited Researchers 2018-Congratulations to Dr Marc Rothenberg! Edward L. Pratt Research Library". prattlibrary.cchmc.org. Retrieved 2021-12-16.
  16. ^ "The American Society for Clinical Investigation Directory".
  17. ^ "About the National Academy of Medicine, Class of 2022".
  18. ^ "Rothenberg Named to National Academy of Medicine". 17 October 2022.
  19. ^ "Four to receive 2023 Daniel Drake Medals from the College of Medicine". 6 April 2023.
  20. ^ "My Bibliography - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2022-04-30.
  21. ^ "Google Scholar, Marc E. Rothenberg, MD, PhD Profile".