John G. Hildebrand is an American neuroscientist, currently Honors Professor and Regents Professor Emeritus at University of Arizona,[1] and has been elected as Fellow of the American Academy of Arts and Sciences, International Society for Neuroethology, Royal Entomological Society of London, American Association for the Advancement of Science and Entomological Society of America, awarded an honorary degree by Universitá degli Studi di Cagliari and named Einstein Professor at Chinese Academy of Sciences.

Education

edit

John Hildebrand graduated from Belmont (Massachusetts) High School in 1960. He earned his baccalaureate degree magna cum laude in Biology at Harvard University in 1964 and his Ph.D. in Biochemistry at Rockefeller University in 1969[2][3][4] He was elected to the American Philosophical Society in 2014.[5]

Career

edit

Hildebrand entered the field of Neurobiology in 1969 as a Helen Hay Whitney Foundation Postdoctoral Research Fellow in the Department of Neurobiology at Harvard Medical School in the laboratory of Professor Edward A. Kravitz. In that department, he advanced from Instructor (1970-1971) to Assistant Professor (1972-1976) and finally Associate Professor (1977-1980) of Neurobiology. In 1980 he accepted an appointment as Professor of Biological Sciences at Columbia University in New York City.

In 1985 he joined the University of Arizona in Tucson as the founding Director of a new Division of Neurobiology in the Arizona Research Laboratories.  The Division became the Department of Neuroscience in the College of Science in 2009, with Hildebrand as its Head until 2013. In 2022, he retired from the faculty.

Research

edit

Hildebrand’s undergraduate research, with Professors John H. Law and Konrad E. Bloch, dealt with the structure of phospholipids in bacteria and resulted in his first publication in 1964.[6] His doctoral thesis research, advised by Professors Leonard B. Spector and Fritz A. Lipmann, provided evidence that succinyl phosphate is a transient intermediate in the substrate-level phosphorylation reaction, catalyzed by the enzyme succinyl-CoA synthetase, in the Citric Acid Cycle of bacteria (Escherichia coli).[7]

Since 1969 his research has focused on sensory neurobiology and neuroethology of experimentally favorable arthropods. First, working with lobsters (Homarus americanus), he led an effort that identified acetylcholine as a sensory neurotransmitter. Since 1972, his multidisciplinary research with his coworkers has combined neurophysiological, behavioral, chemical-ecological, anatomical, molecular and developmental approaches in studies of the olfactory system in insects (mainly the giant sphinx moth Manduca sexta). The goal of this research has been to uncover structural, developmental, and functional principles that may apply to other nervous systems, including those of vertebrate animals. Moreover, this work on Manduca aims to illuminate the olfactory bases of behaviors of other insects, both harmful and beneficial, that impact human health and welfare. He has studied the biology and behavior of Triatomine (“kissing”) bugs living in the Sonoran Desert of Arizona and in South America (where they are vectors of Chagas Disease); and the functional organization of neurosecretory systems.[8]

Honors and awards

edit

References

edit
  1. ^ "John Hildebrand, Ph.D. | Department of Neuroscience". neurosci.arizona.edu. Retrieved 2023-04-11.
  2. ^ Rice, Marlin (March 11, 2021). "American Entomologist". academic.oup.com. Retrieved 2023-04-11.
  3. ^ "John Hildebrand". arizona.edu. Archived from the original on April 23, 2017. Retrieved April 22, 2017.
  4. ^ "Hildebrand, John". aaas.org. Archived from the original on April 23, 2017. Retrieved April 22, 2017.
  5. ^ "APS Member History". search.amphilsoc.org. Retrieved 2021-03-03.
  6. ^ Hildebrand, John G.; Law, John H. (1964-09-01). "Fatty Acid Distribution in Bacterial Phospholipids. The Specificity of the Cyclopropane Synthetase Reaction*". Biochemistry. 3 (9): 1304–1308. doi:10.1021/bi00897a020. ISSN 0006-2960. PMID 14229673.
  7. ^ Hildebrand, J G; Spector, L B (1969). "Succinyl Phosphate and the Succinyl Coenzyme A Synthetase Reaction". Journal of Biological Chemistry. 244 (10): 2606–2613. doi:10.1016/s0021-9258(18)83443-3. ISSN 0021-9258. PMID 4890228.
  8. ^ "John Hildebrand, Ph.D. | Department of Neuroscience". neurosci.arizona.edu. Retrieved 2023-04-13.
  9. ^ Sciences (TWAS), The World Academy of. "Hildebrand, John G." TWAS. Retrieved 2023-04-13.
  10. ^ "John G. Hildebrand". International Science Council. Retrieved 2023-04-13.
  11. ^ "John G. Hildebrand – ABC" (in Brazilian Portuguese). Retrieved 2023-04-13.
  12. ^ "Wigglesworth Memorial Lecture Award | Entomological Society of America". www.entsoc.org. Retrieved 2023-04-13.
  13. ^ "APS Member History". search.amphilsoc.org. Retrieved 2021-03-03.
  14. ^ "Hildebrand reelected to a third term as NAS international secretary | UA@Work". uaatwork.arizona.edu. Retrieved 2023-04-13.
  15. ^ "Professor John Hildebrand Hon.FRES". Royal Entomological Society. Retrieved 2023-04-13.
  16. ^ "Association for Chemoreception Sciences". achems.org. Retrieved 2023-04-13.
  17. ^ "John G. Hildebrand, ESA Fellow (2008) | Entomological Society of America". www.entsoc.org. Retrieved 2023-04-13.
  18. ^ "John Hildebrand Named 'Einstein Scholar' by Chinese Academy of Sciences". University of Arizona News. 2008-04-08. Retrieved 2023-04-11.
  19. ^ "John G. Hildebrand". www.nasonline.org. Retrieved 2023-04-13.
  20. ^ "International Society of Chemical Ecology". www.chemecol.org. Retrieved 2023-04-13.
  21. ^ "Hildebrand, Kennicutt Elected to American Academy of Arts and Sciences". University of Arizona News. 2001-06-22. Retrieved 2023-04-13.
  22. ^ "List of Members". Nationale Akademie der Wissenschaften Leopoldina. Retrieved 2023-04-13.
  23. ^ "Past Officers of ISN". www.neuroethology.org. Retrieved 2023-04-13.
  24. ^ "Elected Fellows | American Association for the Advancement of Science (AAAS)". www.aaas.org. Retrieved 2023-04-13.