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Jessica Connelly is a Professor of Psychology at the University of Virginia.[1] Dr. Connelly's research studies different phenotypes and human diseases on both the genetic and epigenetic level.[2]
Education edit
Dr. Jessica Connelly earned her Bachelor's of Science (BS) in Chemistry, with a focus in Biochemistry, at Stockton College of New Jersey, and first began her research journey as a graduate student in 1997 under Dr. John Luchessi.[3] During this time, she was introduced to epigenetics through the study of dosage compensation of Drosophila melanogaster[2] and epigenetics would come to be her field of choice when starting her own lab at the University of Virginia[3]. In 1999, she went on to start her PhD in Genetics at State University of New York at Stony Brook, where she studied under a yeast epigeneticist, Dr. Rolf Sternglanz[3]. In Sternglanz's lab, Connelly's thesis focused on chromatin compaction regulation transcription in histone code[3]. After completing her PhD in 2004, she earned her Postdoctoral degree at Duke University's Center for Human Genetics, during which time she focused on human genetics and genomics[3]. Her mentors during her Postdoctoral degree at Duke University were statistical geneticist, Dr. Elizabeth Hauser, and human genomicist, Dr. Simon Gregory[3].
Major Contributions edit
Dr. Connelly's lab studies oxytocin, a neuropeptide, and its receptor[2]. Dr. Connelly focuses on DNA methylation of the oxytocin receptor, and how individual differences contribute to differences in behavior[2]. Her research has demonstrated that blood biomarker can be used to estimate gene methylation and transcription state in the brain in an animal model, and that increased DNA methylation leads to decreased gene expression in human brains[2]. Dr. Connelly's lab is also one of few that work with prairie voles, instead of mice or rats, due to their social monogamy that is so rare in rodents, but parallel with humans[2].[4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30]
References edit
- ^ "UVA Psychology".
- ^ a b c d e f "Jessica Connelly, PhD". Conjugate: Illustration and Science Blog. 24 Apr 2024.
- ^ a b c d e f "Education".
- ^ "Parents' behavior influences bonding hormone oxytocin in babies". 16 Oct 2019.
- ^ P, Andrea (5 Nov 2019). "A Mother's Behavior Could Epigenetically Impact Infant Oxytocin Levels".
- ^ Kirkpatrick, Bailey (17 Feb 2015). "DNA Methylation Could Explain How People Respond to Fear and Anger".
- ^ "UVa part of research that helps ID women at risk of postpartum depression". 2 August 2015.
- ^ Carter, Sue (9 Oct 2017). "Oxytocin and the Biology of Love: Too Much of a Good Thing?".
- ^ Campbell, Kate (2016). "What can voles tell us about ourselves?".
- ^ Carter, Sue. "Birth and Beyond: The far reaching influence of Oxytocin" (PDF).
- ^ "Mothers' behavior can have substantial impact in developing oxytocin". 22 Oct 2019.
- ^ "Blood marker spots women at risk for postpartum depression". 28 Jul 2015.
- ^ "Mothers' behavior influences bonding hormone in babies study". 20 Oct 2019.
- ^ "C-section birth impacts prairie vole bonding". 17 Feb 2023.
- ^ "Here's how mothers' behaviour influences bonding hormone in babies". 21 Oct 2019.
- ^ Stanford, Kaitlin (29 Jul 2015). "Could a simple test predict postpartum depression in mothers?".
- ^ "Mothers' behavior can greatly influence child's oxytocin system: Study". 29 Oct 2019.
- ^ "Oxytocin Receptor May Influence Postpartum Depression, Be Potential Biomarker". 29 Jul 2015.
- ^ Wijlaars, Linda (3 Aug 2015). "Epigenetic variation predicts post-natal depression".
- ^ Doctor, Rina Marie (29 Jul 2015). "Marker Found In Human Blood May Help Identify Postpartum Depression Risk".
- ^ Yasinski, Emma (1 Sep 2023). "Parental care may sculpt brain development in prairie voles".
- ^ "Autism Speaks Grants to Fund Epigenetic Studies". 18 Dec 2010.
- ^ Anderson, Kate (24 Oct 2015). "Parents' behavior can have substantial impact on developing oxytocin systems in babies".
- ^ "Possible epigenetic cause for oxytocin insensitivity in autism". Epigenomics. 1 (2): 227–229. 2009. doi:10.2217/epi.09.41.
- ^ "Mothers' behaviour influences bonding hormone oxytocin in babies". 18 Nov 2019.
- ^ "Parents' Behavior can Influence Bonding Hormone Oxytocin in Babies". 25 Oct 2019.
- ^ "Study: Hormone Level Predicts How the Brain Processes Social Information". 30 Mar 2015.
- ^ Samarrai, Farris (30 Mar 2015). "Hormone level predicts how the brain processes social information".
- ^ "Sex/gender in autism". 19 Oct 2015.
- ^ "Postpartum Depression May Be Predicted with a Blood Test".