In pharmacology and medicine, dosage refers to the prescribed regimen for administering a medication or substance, encompassing the amount, frequency, and duration of use.[1] It is distinct from dose, which denotes a single, specific quantity of a drug or substance given at one time.[2] Dosage typically includes information on the number of doses, intervals between administrations, and the overall treatment period.[3] For example, a dosage might be described as "200 mg twice daily for two weeks," where 200 mg represents the individual dose, twice daily indicates the frequency, and two weeks specifies the duration of treatment.[4]
References
edit- ^ Rowbotham S, Conte K, Hawe P (June 2019). "Variation in the operationalisation of dose in implementation of health promotion interventions: insights and recommendations from a scoping review". Implementation Science. 14 (1): 56. doi:10.1186/s13012-019-0899-x. PMC 6555031. PMID 31171008.
- ^ Tyson RJ, Park CC, Powell JR, Patterson JH, Weiner D, Watkins PB, Gonzalez D (2020). "Precision Dosing Priority Criteria: Drug, Disease, and Patient Population Variables". Frontiers in Pharmacology. 11: 420. doi:10.3389/fphar.2020.00420. PMC 7188913. PMID 32390828.
- ^ Choudhary D, Goykar H, Kalyane D, Desai N, Tekade RK (January 2021). "Dose, dosage regimen, and dose adjustment in organ failure.". Biopharmaceutics and pharmacokinetics considerations. Academic Press. pp. 29–82. doi:10.1016/B978-0-12-814425-1.00004-8. ISBN 978-0-12-814425-1.
- ^ Korn EL, Moscow JA, Freidlin B (May 2023). "Dose optimization during drug development: whether and when to optimize". Journal of the National Cancer Institute. 115 (5): 492–497. doi:10.1093/jnci/djac232. PMC 10165487. PMID 36534891.
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