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Dihydrotachysterol (DHT) is a synthetic vitamin D analog activated in the liver that does not require renal hydroxylation like vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). DHT has a rapid onset of action (2 hours), a shorter half-life, and a greater effect on mineralization of bone salts than does vitamin D.[1]

Dihydrotachysterol
Structural formula
Space-filling model of the dihydrotachysterol molecule
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa682335
ATC code
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
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ECHA InfoCard100.000.611 Edit this at Wikidata
Chemical and physical data
FormulaC28H46O
Molar mass398.664 g/mol g·mol−1
3D model (JSmol)
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ReferencesEdit

  1. ^ R. Gagnon; G. W. Ogden; G. Just; M. Kaye (1974). "Comparison of Dihydrotachysterol and 5,6-trans Vitamin D3 on Intestinal Calcium Absorption in Patients with Chronic Renal Failure". Canadian Journal of Physiology and Pharmacology. 52 (2): 272–274. doi:10.1139/y74-037. PMID 4365509.