Dieter Seebach

Dieter Seebach is a German chemist known for his synthesis of biopolymers and dendrimers, and for his contributions to stereochemistry. He was born on 31 October 1937 in Karlsruhe. He studied chemistry at the University of Karlsruhe (TH) under the supervision of Rudolf Criegee and at Harvard University with Elias Corey finishing in 1969. After his habilitation he became professor for organic chemistry at the University of Giessen. After six years he was appointed professor at the ETH Zurich where he worked until he retired in 2003.

Dieter Seebach
Seebach, Dieter (* 31. Oktober 1937 in Karlsruhe).jpg
Dieter Seebach
Born (1937-10-31) 31 October 1937 (age 83)
Alma materUniversity of Karlsruhe (TH)
Harvard University
AwardsMarcel Benoist Prize (2000)
The Ryoji Noyori Prize (2004)
Tetrahedron Prize (2003)
Arthur C. Cope Award (2019)
Scientific career
InstitutionsUniversity of Karlsruhe (TH)
University of Giessen
ETH Zurich
Doctoral advisorRudolf Criegee
Doctoral studentsDieter Enders, Paul Knochel
InfluencedElias James Corey


Seebach worked on dendrimer chemistry and on the synthesis of beta-peptides.[1][2] The development of the umpolung, a polarity inversion of the carbonyl group, with 1,3-propanedithiol together with Corey had a big influence on organic synthesis, and subsequently the Corey-Seebach reaction was named after them.[3]

The Fráter–Seebach alkylation, a diastereoselective reaction of beta-hydroxy esters, is named after him.


See alsoEdit


  1. ^ Hook, David F. (2004). "Celebrating Dieter Seebach's Contributions to Science: A Bitter Sweet Occasion?". Chimia. 58 (2): 321–324. doi:10.2533/000942904777677876.
  2. ^ Dieter Seebach and Jennifer L. Matthews (1997). "β-Peptides: a surprise at every turn". Chem. Commun. (21): 2015–2022. doi:10.1039/a704933a.
  3. ^ Seebach D., Corey E. J. (1975). "Generation and synthetic applications of 2-lithio-1,3-dithianes". Journal of Organic Chemistry. 40 (2): 231–237. doi:10.1021/jo00890a018.
  4. ^ "Past laureates – Marcel Benoist Foundation".
  5. ^ "Tetrahedron".
  6. ^ "Ryoji Noyori Prize | SSOCJ | the Society of Synthetic Organic Chemistry, Japan".
  7. ^ "2019 Cope and Cope Scholar Award winners".

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