Diego Fernández de Córdoba may refer to:
- Diego Fernández de Córdoba (1355–1435), lord of Baena
- Diego Fernández de Córdoba y Montemayor (died 1481), counsellor of King Henry IV of Castile
- Diego Fernández de Córdoba y Carrillo de Albornoz (died 1487), counsellor of King Henry IV of Castile
- Diego Fernández de Córdoba y Arellano, marqués de Comares (1463–1518), Governor of Oran and Mazalquivir and first Viceroy of Navarre
- Diego Fernández de Córdoba y Mendoza, 3rd Count of Cabra, (fl. 1487–1525)
- Diego Fernández de Córdoba, 1st Marquess of Guadalcázar (1578–1630)
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