Dera Ismail Khan bombing may refer to:
- January 2007 Dera Ismail Khan suicide bombing
- August 2008 Dera Ismail Khan suicide bombing
- November 2008 Dera Ismail Khan bombing
- January 2009 Dera Ismail Khan bombings
- February 2009 Dera Ismail Khan suicide bombing
- May 2009 Dera Ismail Khan bombings
- 2010 Dera Ismail Khan bombing
- 2012 Dera Ismail Khan bombing
- 2017 Dera Ismail Khan bombing
- 2023 Dera Ismail Khan bombing