David Syme (1827–1908) was a Scottish-Australian newspaper proprietor (The Age).
David Syme may also refer to:
- David Syme (footballer) (born 1997), Scottish footballer for Cowdenbeath, formerly of Kilmarnock and Partick Thistle
- David Syme (pianist) (born 1949), American pianist
- David Syme (referee) (1944–2020), Scottish football referee
This disambiguation page lists articles about people with the same name.
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