DOS 5 or DOS-5 may refer to:
- The Soviet space station Salyut 6
- DOS 5 (OS/2), one of the early project names for the then still unreleased IBM and Microsoft OS/2 1.0 between 1985 and 1987
- DR DOS 5.0
- MS-DOS 5.x, by Microsoft
- IBM PC DOS 5.x, by IBM
See also
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