DFN is a three letter acronym that may refer to:
- Dehcho First Nations, one of the First Nations of North Western Canada
- Desert Fireball Network, a fireball camera network based in Australia
- Deutsches Forschungsnetz, the German national research and education network
<dfn>
, Definition HTML tag- Differential Frequency Noise (electronics)
- Dignity Freedom Network, formerly the Dalit Freedom Network
- Direct function (dfn), a way to define a function in the APL programming language
- Dual Flat No Lead, a style of integrated circuit package