DFE or DfE may refer to:
Organizations edit
- Department for the Economy, Northern Ireland
- Department for Education, UK
- DePatie–Freleng Enterprises, a defunct animation company
Science edit
- Dilated fundus examination of the eye
- Distribution of fitness effects
- Dietary folate equivalent, bioavailability of folate
Technology edit
- Design-focused evaluation of educational quality
- Design for the Environment of a product or service
- DFE Ascender, an ultralight aircraft
Other edit
- Dragon Fli Empire, a Canadian hip hop group
- Dunfermline Town railway station, Scotland, National Rail station code