Chlorantraniliprole

Chlorantraniliprole (Rynaxpyr) is an insecticide of the ryanoid class.[1] Chlorantraniliprole is being developed world-wide by DuPont belonging to a new class of selective insecticides featuring a novel mode of action to control a range of pests belonging to the order Lepidoptera and some other Coleoptera, Diptera and Isoptera species.

Chlorantraniliprole
Chlorantraniliprole.png
Names
IUPAC name
5-bromo-N-[4-chloro-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloropyridin-2-yl)pyrazole-3-carboxamide
Other names
Rynaxpyr
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ECHA InfoCard 100.112.607
EC Number
  • 610-489-8
KEGG
UNII
Properties
C18H14BrCl2N5O2
Molar mass 483.15 g·mol−1
Hazards
GHS pictograms GHS07: HarmfulGHS09: Environmental hazard
GHS Signal word Warning
H319, H335, H400, H410
P261, P264, P271, P273, P280, P304+340, P305+351+338, P312, P337+313, P391, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Chlorantraniliprole activates Ryanodine receptor via stimulation of the release of calcium stores from the Sarcoplasmic reticulum of muscle cells ( i.e. for chewing insect pest) causing impaired regulation, paralysis and ultimately death of sensitive species. The differential selectivity Chlorantraniliprole had towards insect rynodine receptors explained the outstanding profile of low mammalian toxicity. Chlorantraniliprole is active on chewing pest insects primarily by ingestion and secondarily by contact.

As active ingredient (a.i.) in insecticide -

a. Chlorantraniliprole 0.4% GR having the trade name Ferterra.

b. Chlorantraniliprole 18.5% SC having the trade name Coragen.

ReferencesEdit