Cer6 is a LTR retrotransposon that is described from sequencing data in the chromosome III of C. elegans.[1][2][3]
LTR retrotransposons
editLTR retrotransposons are class I transposable element characterized by the presence of long terminal repeats (LTRs) directly flanking an internal coding region. As retrotransposons, they mobilize through reverse transcription of their mRNA and integration of the newly created cDNA into another location. Their mechanism of retrotransposition is shared with retroviruses, with the difference that most LTR-retrotransposons do not form infectious particles that leave the cells and therefore only replicate inside their genome of origin.
References
edit- ^ Nathan J. Bowen; John F. McDonald (1999). "Genomic Analysis of Caenorhabditis elegans Reveals Ancient Families of Retroviral-like Elements". Genome Res. 9 (10). Cold Spring Harbor Laboratory Press: 924–935. doi:10.1101/gr.9.10.924. PMID 10523521.
- ^ N J Bowen; J F McDonald (2001). "Drosophila euchromatic LTR retrotransposons are much younger than the host species in which they reside". Genome Res. 11 (9): 1527–40. doi:10.1101/gr.164201. PMC 311128. PMID 11544196.
- ^ Eric W. Ganko; Kevin T. Fielman; John F. McDonald (2001). "Evolutionary History of Cer Elements and Their Impact on the C. elegans Genome". Genome Res. 11 (12): 2066–2074. doi:10.1101/gr.196201. PMC 311226. PMID 11731497.
Further reading
edit- Snyder, L.; Champness, W. (2003). "Ch. 9: Transposition and site-specific recombination". Molecular Genetics of Bacteria (2nd ed.). Washington DC: ASM Press. pp. 303–340. ISBN 1-55581-204-X.
- "Bibliography: Transposons as a genetic tool". Citizendium.org.
- Martienssen, R.A.; Springer, P.S. "Enhancer and Gene Trap Transposon Mutagenesis in Arabidopsis". Cold Spring Harbor Laboratory.
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