In molecular biology, CagZ is a protein produced by Helicobacter pylori (Campylobacter pylori). It is a 23 kDa protein consisting of a single compact L-shaped domain, composed of seven alpha-helices that run antiparallel to each other. 70% of the amino acids are in alpha-helix conformation and no beta-sheet is present. CagZ is essential for the translocation of the pathogenic protein CagA into host cells.[1]

CagZ
crystal structure of cag-z from helicobacter pylori
Identifiers
SymbolCagZ
PfamPF09053
InterProIPR015139
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

References

edit
  1. ^ Cendron L, Seydel A, Angelini A, Battistutta R, Zanotti G (July 2004). "Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system". J. Mol. Biol. 340 (4): 881–9. doi:10.1016/j.jmb.2004.05.016. PMID 15223328.
This article incorporates text from the public domain Pfam and InterPro: IPR015139