C48 or C-48 may refer to:
- C-48 (Michigan county highway)
- C48 road (Namibia)
- Bill C-48, various legislation of the Parliament of Canada
- Caldwell 48, a spiral galaxy
- Douglas C-48, an American military transport
- Four Knights Game, a chess opening
- HMS Gambia (C48), a Fiji-class light cruiser of the Royal Navy
This disambiguation page lists articles associated with the same title formed as a letter–number combination.
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