KIF16B

Kinesin family member 16B, also known as KIF16B, is a protein which in humans is encoded by the KIF16B gene.

KIF16B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2V14
Identifiers
Aliases	KIF16B, C20orf23, KISC20ORF, SNX23, kinesin family member 16B
External IDs	OMIM: 618171; MGI: 1098240; HomoloGene: 135708; GeneCards: KIF16B; OMA:KIF16B - orthologs
Gene location (Human) Chr. Chromosome 20 (human) Band 20p12.1 Start 16,272,104 bp End 16,573,448 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2|2 G1 Start 142,617,474 bp End 142,901,531 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve jejunal mucosa mucosa of colon mucosa of sigmoid colon Achilles tendon mucosa of transverse colon rectum left adrenal gland left adrenal cortex right adrenal cortex Top expressed in submandibular gland seminal vesicula parotid gland sternocleidomastoid muscle stria vascularis intercostal muscle vastus lateralis muscle digastric muscle triceps brachii muscle lacrimal gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding microtubule motor activity phosphatidylinositol-3-phosphate binding microtubule binding phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-3,4-bisphosphate binding phosphatidylinositol binding plus-end-directed microtubule motor activity ATP binding phosphatidylinositol-3,4,5-trisphosphate binding lipid binding ATPase activity Cellular component cytoplasm endosome early endosome membrane membrane kinesin complex early endosome microtubule cytoskeleton cytosol phagocytic vesicle Biological process endoderm development epidermal growth factor receptor signaling pathway Golgi to endosome transport receptor catabolic process fibroblast growth factor receptor signaling pathway microtubule-based movement early endosome to late endosome transport formation of primary germ layer regulation of receptor recycling cellular response to interferon-gamma Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55614 16558 Ensembl ENSG00000089177 ENSMUSG00000038844 UniProt Q96L93 B1AVY7 RefSeq (mRNA) NM_001199865 NM_001199866 NM_024704 NM_001081133 NM_001355123 RefSeq (protein) NP_001186794 NP_001186795 NP_078980 NP_001074602 NP_001342052 Location (UCSC) Chr 20: 16.27 – 16.57 Mb Chr 2: 142.62 – 142.9 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

See also

• Kinesin

Further reading

• Seet LF, Hong W (2006). "The Phox (PX) domain proteins and membrane traffic". Biochim. Biophys. Acta. 1761 (8): 878–96. doi:10.1016/j.bbalip.2006.04.011. PMID 16782399.
• Miki H, Okada Y, Hirokawa N (2005). "Analysis of the kinesin superfamily: insights into structure and function". Trends Cell Biol. 15 (9): 467–76. doi:10.1016/j.tcb.2005.07.006. PMID 16084724.
• Worby CA, Dixon JE (2003). "Sorting out the cellular functions of sorting nexins". Nat. Rev. Mol. Cell Biol. 3 (12): 919–31. doi:10.1038/nrm974. PMID 12461558. S2CID 36361630.
• Vasilescu J, Zweitzig DR, Denis NJ, et al. (2007). "The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells". J. Proteome Res. 6 (1): 298–305. CiteSeerX 10.1.1.401.4220. doi:10.1021/pr060438j. PMID 17203973.
• Hoepfner S, Severin F, Cabezas A, et al. (2005). "Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B". Cell. 121 (3): 437–50. doi:10.1016/j.cell.2005.02.017. PMID 15882625. S2CID 16764713.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
• Nagase T, Kikuno R, Nakayama M, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (4): 273–81. doi:10.1093/dnares/7.4.271. PMID 10997877.

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Kinesin-like protein KIF16B