Blast2GO, first published in 2005,[1][2][3][4] is a bioinformatics software tool for the automatic, high-throughput functional annotation of novel sequence data (genes proteins). It makes use of the BLAST[5] algorithm to identify similar sequences to then transfers existing functional annotation from yet characterised sequences to the novel one. The functional information is represented via the Gene Ontology (GO), a controlled vocabulary of functional attributes. The Gene Ontology, or GO, is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species.[6]

Blast2GO Logo.png
TypeBioinformatics Software
Inception2011 (2011)
ManufacturerBioBam Bioinformatics
Models madeDemo, Basic, Trial, Pro, Plugin, Commandline

See alsoEdit


  1. ^ Conesa, A; Götz, S; García-Gómez, JM; Terol, J; Talón, M; Robles, M (Sep 15, 2005). "Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research". Bioinformatics. 21 (18): 3674–6. doi:10.1093/bioinformatics/bti610. PMID 16081474.
  2. ^ Götz, S; García-Gómez, JM; Terol, J; Williams, TD; Nagaraj, SH; Nueda, MJ; Robles, M; Talón, M; Dopazo, J; Conesa, A (June 2008). "High-throughput functional annotation and data mining with the Blast2GO suite". Nucleic Acids Research. 36 (10): 3420–35. doi:10.1093/nar/gkn176. PMC 2425479. PMID 18445632.
  3. ^ Conesa, A; Götz, S (2008). "Blast2GO: A comprehensive suite for functional analysis in plant genomics". International Journal of Plant Genomics. 2008: 1–12. doi:10.1155/2008/619832. PMC 2375974. PMID 18483572.
  4. ^ Götz, S; Arnold, R; Sebastián-León, P; Martín-Rodríguez, S; Tischler, P; Jehl, MA; Dopazo, J; Rattei, T; Conesa, A (Apr 1, 2011). "B2G-FAR, a species-centered GO annotation repository". Bioinformatics. 27 (7): 919–24. doi:10.1093/bioinformatics/btr059. PMC 3065692. PMID 21335611.
  5. ^ Altschul, SF; Gish, W; Miller, W; Myers, EW; Lipman, DJ (Oct 5, 1990). "Basic local alignment search tool". Journal of Molecular Biology. 215 (3): 403–10. doi:10.1016/S0022-2836(05)80360-2. PMID 2231712.
  6. ^ The Gene Ontology Consortium (January 2008). "The Gene Ontology project in 2008". Nucleic Acids Res. 36 (Database issue): D440–4. doi:10.1093/nar/gkm883. PMC 2238979. PMID 17984083.

External linksEdit

  • Official website Blast2GO - Tool for functional annotation of (novel) sequences and the analysis of annotation data.
  • Company developing Blast2GO — BioBam Bioinformatics S.L., a bioinformatics company dedicated to creating user-friendly software for the scientific community is developing, maintaining and distributing Blast2GO.
  • Gene Ontology Tools — Provides access to the ontologies, software tools, annotated gene product lists, and reference documents describing the GO and its uses.
  • PlantRegMap—Plant GO annotation for 165 species and GO enrichment analysis