Big Up may refer to:
- Big Up (group), a Black gay men's group that merged with GMFA
- "Big Up" (Shaggy song), a song by Shaggy
- "Big Up" (Avalon song), 2005 song by Swedish duo group Avalon
- Big Ups (band), American musical band
- Big UP Productions, American film production company
- The Big Up Festival, a festival of music, art and culture in Ghent, New York
This disambiguation page lists articles associated with the title Big Up.
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