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Mitochondrial pyruvate carrier 2

  (Redirected from BRP44)

Mitochondrial pyruvate carrier 2 (MPC2) also known as brain protein 44 (BRP44) is a protein that in humans is encoded by the MPC2 gene.[5][6][7] It is part of the Mitochondrial Pyruvate Carrier (MPC) protein family. [8] This protein is involved in transport of pyruvate across the inner membrane of mitochondria in preparation for the pyruvate dehydrogenase reaction. [9]

MPC2
Identifiers
AliasesMPC2, BRP44, mitochondrial pyruvate carrier 2, SLC54A2
External IDsOMIM: 614737 MGI: 1917706 HomoloGene: 31675 GeneCards: MPC2
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for MPC2
Genomic location for MPC2
Band1q24.2Start167,916,675 bp[1]
End167,937,072 bp[1]
RNA expression pattern
PBB GE BRP44 202427 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001143674
NM_015415

NM_027430

RefSeq (protein)

NP_001137146
NP_056230

NP_081706

Location (UCSC)Chr 1: 167.92 – 167.94 MbChr 1: 165.46 – 165.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactive pathway mapEdit

Click on genes, proteins and metabolites below to link to respective articles. [§ 1]

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|{{{bSize}}}px|alt=Glycolysis and Gluconeogenesis edit]]
Glycolysis and Gluconeogenesis edit
  1. ^ The interactive pathway map can be edited at WikiPathways: "GlycolysisGluconeogenesis_WP534".

ReferencesEdit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000143158 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026568 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  6. ^ Tsou AP, Lai C, Danielson P, Noonan DJ, Sutcliffe JG (Dec 1986). "Structural characterization of a heterogeneous family of rat brain mRNAs". Mol Cell Biol. 6 (3): 768–78. PMC 367577. PMID 3022128.
  7. ^ "Entrez Gene: BRP44 brain protein 44".
  8. ^ https://www.uniprot.org/uniprot/?query=family:%22mitochondrial+pyruvate+carrier+%28MPC%29+%28TC+2.A.105%29+family%22
  9. ^ https://www.ebi.ac.uk/QuickGO/term/GO:0050833

Further readingEdit