The son of Aulus Plautius who was praetor urbanus in 51 BC, Plautius was appointed consul suffectus in 1 BC, replacing Cossus Cornelius Lentulus Gaetulicus. It has been speculated that he may have been the Aulus Plautius who was sent to Apulia by Augustus possibly around AD 9/10, with the task of interrogating and torturing slaves for some purpose, although it is more likely that this refers to his son Aulus Plautius who may have been involved with the suppression of a slave revolt in Apulia in AD 24.
Aulus Plautius was married to Vitellia, the grandaunt of the future Roman emperor Vitellius. They had at least two sons and one daughter: Aulus Plautius (suffect consul in 29 and who initiated the conquest of Britannia); Quintus Plautius (ordinary consul in 36), and Plautia, who was the wife of Publius Petronius.
- Giuseppe Camodeca: Problemi di storia sociale in Alife Romana. Le gentes senatorie degli Aedii e dei Granii e i ceti dirigenti del primo principato. In: Luigi Di Cosmo (Hrsg.): Il territorio Alifano. Archeologia, arte, storia. Atti del convegno, S. Angelo d’Alife, 26 aprile 1987. S. Angelo d’Alife 1990. S. 123–143.
- Werner Eck, Antonio Caballos, Fernando Fernández: Das Senatus consultum de Cn. Pisone patre. Beck, München 1996, ISBN 3-406-41400-1, S. 105−106.
- Prosopographia Imperii Romani (PIR²). 1998, P 456.