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Alphabaculovirus is a genus of viruses in the family Baculoviridae.[1] Its natural hosts include a wide range of invertebrates, among them winged insects, Lepidopterans, Hymenopterans, Dipterans, and decapods. There are currently 47 species in the genus, including the type species Autographa californica multiple nucleopolyhedrovirus.[2][3]

Virus classification
Group I (dsDNA)
Type Species



Viruses in Alphabaculovirus are enveloped, with circular genomes around 80–180 kbp in length. The genome codes for 100 to 180 proteins.[3]

Genus Structure Symmetry Capsid Genomic arrangement Genomic segmentation
Alphabaculovirus Budded or Occluded Enveloped Circular Monopartite

Life cycleEdit

Alphabaculovirus replication is nuclear. Entry into the host cell is achieved by attachment of the viral glycoproteins to host receptors, which mediates endocytosis. Replication follows the double-stranded DNA bidirectional replication model. DNA-templated transcription with some alternative splicing mechanism is the method of transcription. Translation takes place by leaky scanning. The virus exits the host cell by nuclear pore export and exists in occlusion bodies after cell death, remaining infectious until finding another host. Winged insects, arthropods, Lepidoptera, Hymenoptera, Diptera, and Decapoda serve as natural hosts. Transmission routes are fecal-oral.[3]

Genus Host details Tissue tropism Entry details Release details Replication site Assembly site Transmission
Alphabaculovirus Winged insects Midgut then hemocoel; digestive gland epithelium (shrimps) Glycoproteins Budding; Occlusion Nucleus Nucleus Oral-fecal


  1. ^ Harrison, RL; Herniou, EA; Jehle, JA; Theilmann, DA; Burand, JP; Becnel, JJ; Krell, PJ; van Oers, MM; Mowery, JD; Bauchan, GR; Ictv Report, Consortium (September 2018). "ICTV Virus Taxonomy Profile: Baculoviridae". The Journal of General Virology. 99 (9): 1185–1186. doi:10.1099/jgv.0.001107. PMID 29947603.
  2. ^ "ICTV Report". ICTV Report Baculoviridae.
  3. ^ a b c "Viral Zone". ExPASy. Retrieved 12 June 2015.

External linksEdit