Akisada (written: 秋定) is a Japanese surname. Notable people with the surname include:
- Rio Akisada (秋定 里穂, born 1982), Japanese actress
Akisada (written: 顕定) is also a masculine Japanese given name. Notable people with the name include:
- Uesugi Akisada (上杉 顕定, 1454–1510), Japanese samurai