Adéfọpẹ́ is a Yoruba surname meaning "the crown or royalty grants thanksgivings". Notable people with the surname include:
- Henry Adefope (1926–2012), Nigerian politician
- Lolly Adefope (born 1990), English stand-up comedian and actress
Adéfọpẹ́ is a Yoruba surname meaning "the crown or royalty grants thanksgivings". Notable people with the surname include: