AZD0328

AZD0328
Legal status
Legal status	Investigational;
Identifiers
	IUPAC name 3′H-4-Azaspiro[bicyclo[2.2.2]octane-2,2'-furo[2,3-b]pyridine];
CAS Number	220099-91-2 ;
PubChem CID	9794392;
ChemSpider	7970159 ;
UNII	2B218X5QIY;
ChEMBL	ChEMBL2151437 ;
CompTox Dashboard (EPA)	DTXSID40944616 ;
Chemical and physical data
Formula	C13H16N2O
Molar mass	216.284 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1C2=CC=CN=C2OC11CN2CCC1CC2;
	InChI InChI=1S/C13H16N2O/c1-2-10-8-13(16-12(10)14-5-1)9-15-6-3-11(13)4-7-15/h1-2,5,11H,3-4,6-9H2/t13-/m0/s1 ; Key:OCKIPDMKGPYYJS-ZDUSSCGKSA-N ;
	(what is this?) (verify)

AZD0328 is an experimental drug. It is a selective α7 nicotinic receptor agonist that enhances cortical dopamine release and improves learning and attentional processes in rats.^[1]

References edit

^ Sydserff S, Sutton EJ, Song D, Quirk MC, Maciag C, Li C, et al. (October 2009). "Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes". Biochemical Pharmacology. 78 (7): 880–8. doi:10.1016/j.bcp.2009.07.005. PMID 19615981.

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[1] Sydserff S, Sutton EJ, Song D, Quirk MC, Maciag C, Li C, et al. (October 2009). "Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes". Biochemical Pharmacology. 78 (7): 880–8. doi:10.1016/j.bcp.2009.07.005. PMID 19615981.

[1]

Legal status

Legal status	Investigational
Identifiers
IUPAC name 3′H-4-Azaspiro[bicyclo[2.2.2]octane-2,2'-furo[2,3-b]pyridine]
CAS Number	220099-91-2^Y
PubChem CID	9794392
ChemSpider	7970159^Y
UNII	2B218X5QIY
ChEMBL	ChEMBL2151437^Y
CompTox Dashboard (EPA)	DTXSID40944616
Chemical and physical data
Formula	C₁₃H₁₆N₂O
Molar mass	216.284 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1C2=CC=CN=C2OC11CN2CCC1CC2
InChI InChI=1S/C13H16N2O/c1-2-10-8-13(16-12(10)14-5-1)9-15-6-3-11(13)4-7-15/h1-2,5,11H,3-4,6-9H2/t13-/m0/s1^Y Key:OCKIPDMKGPYYJS-ZDUSSCGKSA-N^Y
^NY (what is this?) (verify)